[Remote] Software Engineer - .NET Full Stack Developer

Note: The job is a remote job and is open to candidates in USA. Mayo Clinic Rochester is seeking a Software Engineer to design, develop, and maintain .NET-based back-end services for genomics and clinical applications. The role involves building and optimizing services for genomic workflows and collaborating with cross-functional teams to ensure high performance and reliability of the systems.

Responsibilities

• Designing and implementing services aligned to enterprise architecture, including cloud-ready APIs, data integration pipelines, and secure interoperability layers for genomic systems
• Building and optimizing services that handle complex genomic workflows, large-scale clinical datasets, and high-throughput data processing
• Ensuring that all services meet strict performance, reliability, and accuracy requirements, scale effectively as data volumes grow, and remain resilient within hybrid cloud ecosystems
• Participating in Agile and DevOps practices using GitHub, Azure DevOps (ADO), Azure Pipelines, and CI/CD frameworks
• Maintaining comprehensive technical documentation, contributing to code reviews, and participating in expert-level troubleshooting through log analysis, root cause evaluation, and data/system investigation

Skills

• Bachelor's degree in computer science/engineering or related field; Or an associate's degree in computer science/engineering or related field with an additional 2 years of experience as described below
• Have working knowledge and experience of Software Engineering with a minimum of internships and a minimum of 1 year of experience, or 2 years of experience coding applications or services in a high-level language (C, C++, Golang, Java, C# etc.)
• Demonstrated problem solving and time management skills
• Possesses strong technical aptitude for designing and implementing software solutions
• Experience with modern application development frameworks
• Knowledge of professional software engineering practices & best practices for the full software development life cycle, including coding standards, code reviews, source control management, build processes, testing, and operations
• Deep hands-on technical expertise, excellent verbal and written communication skills
• Experience with Agile software development techniques
• Experience developing applications in hybrid environments, including on-premises systems, Azure, and Google Cloud Platform (GCP)
• Familiarity with building and integrating RESTful APIs, microservices, and web services using .NET technologies
• Knowledge of DevOps pipelines and CI/CD using Azure DevOps, GitHub Actions, or Azure Pipelines
• Utilization of AI coding tool such as GitHub CoPilot, Gemini, Claude
• Experience with relational and NoSQL databases, analytics platforms, big-data processing, or enterprise data pipelines
• Background in developing high-performance, scalable, and highly available distributed systems
• Experience supporting or developing solutions in healthcare, clinical, Bioinformatics or genomics-focused applications is highly desirable
• Ability to use a wide variety of open-source technologies and cloud-based services
• Experience with Google and Azure cloud environments
• Experience in databases, analytics, big data systems or business intelligence products
• Experience with building high-performance, highly available and scalable distributed systems
• Experience developing software for healthcare related industries

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