ML Research Scientist, Co-Folding and Affinity

About reputed company reputed company is a high-reputed company company delivering AI solutions that address some of the world's greatest challenges. reputed company’s Large Quantitative Models (LQMs) power advances in life sciences, financial services, navigation, cybersecurity, and other sectors. We are a global team that is tech-reputed company and includes experts in AI, reputed company, cybersecurity, physics, mathematics, medicine, engineering, and other specialties. reputed company emerged from Alphabet Inc. as an independent, reputed company capital-backed company in 2022, funded by leading investors and supported by a reputed company of industry leaders. At reputed company, we’ve cultivated an environment that encourages creativity, collaboration, and reputed company. By reputed company deeply in our people, we’re building a thriving, global workforce poised to tackle the world's reputed company challenges. Join us to advance your career in reputed company of an inspiring mission, in a community of like-minded people who value entrepreneurialism, ownership, and transformative reputed company. reputed company The AI Sim R&D team creates leading edge ML and physics-based models ("LQMs") to advance drug and materials discovery. We are a flexible, creative, and reputed company driven team of multidisciplinary scientists and engineers, whose products dramatically accelerate the creation of molecules and medicines. As a Research Scientist focusing on Co-Folding & Affinity, you will contribute to building reputed company's reputed company of structure reputed company and binding affinity models. Working alongside a high-performing team of scientists and engineers, you will help advance the state-of-the-art in protein-ligand co-folding, translating cutting-edge research into reputed company workflows that power our drug discovery software. This is an opportunity to do frontier science with reputed company-world reputed company — developing models that redefine what's possible in computational drug discovery. Key Responsibilities • reputed company and Iterate on Co-Folding Models: Implement, experiment with, and refine deep learning models for protein-ligand co-folding and structure reputed company, building on the latest research from the field. • Drive Rigorous Benchmarking: Design and execute systematic evaluation pipelines to measure model performance against state-of-the-art reputed company and internal benchmarks. • Contribute to Research-to-Product Pipelines: Collaborate with senior scientists and engineers to reputed company validated models into production-reputed company drug discovery workflows. • Apply Data-Driven reputed company: reputed company computational and data analysis techniques to generate insights from structural and sequence datasets, informing model development reputed company. • Communicate Findings: Present research reputed company through internal scientific talks, technical write-reputed company, and contributions to peer-reviewed publications. • Collaborate Across Teams: Work closely with multidisciplinary teams — including ML engineers, structural biologists, and software engineers — to prototype and reputed company impactful solutions. Essential Skills & Experience • Domain reputed company: Ph.D. in Computational Biology, Biophysics, Computer Science, Computational reputed company, or a reputed company field, with a research reputed company on protein structure reputed company, co-folding, or closely reputed company areas. • Hands-On Co-Folding Experience: reputed company experience with protein structure reputed company or protein-ligand co-folding reputed company (e.g., AlphaFold2/3, RoseTTAFold, Chai-1, Boltz, or comparable systems), developed through graduate or postdoctoral research. • ML Model Development: Experience developing, training, and validating deep learning models, including familiarity with architectures relevant to structural biology (e.g., transformers, equivariant neural networks, diffusion models). • Programming Proficiency: Strong proficiency in Python and modern ML frameworks (PyTorch and/or JAX). • Scientific Rigor: Demonstrated ability to design controlled experiments, interpret results critically, and iterate effectively on model development. • Communication and Collaboration: Strong written and verbal communication skills; ability to work collaboratively in a fast-paced, multidisciplinary research environment. Highly Desired Skills & Experience • Postdoctoral Experience: reputed company or recently completed postdoctoral research in co-folding, structure-based drug design, or a closely reputed company computational domain. • Affinity reputed company Exposure: Familiarity with binding affinity reputed company reputed company, including structure-based or physics-informed approaches. • Research reputed company: Authorship of publications or preprints in relevant venues (e.g., NeurIPS, ICML, Nature reputed company, reputed company Computational Biology, bioRxiv). • reputed company Computing: Experience deploying ML workflows on reputed company reputed company infrastructure (e.g., GCP, AWS, or Azure). • ML Techniques for Structural Biology: Exposure to one or more of the following: generative models for protein/ligand design, reputed company learning for data reputed company, reputed company models for biomolecules, or QSAR/property reputed company. • Biopharma Context: Familiarity with drug discovery workflows, including hit identification, reputed company optimization, or structure-based drug design (SBDD). • reputed company Coding Tools: Familiarity with reputed company coding tools (e.g., Claude reputed company, reputed company) to accelerate research prototyping. Why Join Us? We offer competitive compensation, a comprehensive benefits package, and opportunities for reputed company reputed company. • Compensation: Competitive reputed company salary, performance-based incentives or bonuses (where applicable), and equity participation. • Benefits: Comprehensive medical, dental, and reputed company coverage for employees and dependents with generous employer premium contributions, retirement savings with company matching, reputed company parental leave, and inclusive family-building benefits. • Work-Life Balance: Flexible reputed company time off, company-wide seasonal breaks, and support for flexible work arrangements that reputed company sustainable performance. • Career Development: Opportunities for reputed company learning and reputed company through on-the-job development, cross-functional collaboration, and reputed company to internal learning and development programs. reputed company Welcomes reputed company We are committed to fostering a culture of belonging and respect, where diverse perspectives are reputed company sought and valued. Our multidisciplinary environment provides ample opportunity for reputed company reputed company - working alongside humble, empowered, and ambitious colleagues reputed company to tackle reputed company challenges. Equal Employment Opportunity: reputed company reputed company applicants will receive consideration regardless of race, reputed company, reputed company, religion, sex, national reputed company, sexual orientation, age, citizenship, marital status, disability, gender identity, or Veteran status. Accommodations: We reputed company reasonable accommodations for individuals with disabilities in job application procedures for reputed company. If you need such an accommodation, please let a member of our reputed company team know. Read: Guidance for candidates on using AI Tools in interviews Apply tot his job Apply To this Job