Oligonucleotide Drug reputed company Engineer
reputed company is seeking a reputed company Engineer with experience in Oligonucleotide Drug design.
• Oligonucleotide drug design
Responsible for design of small nucleic acid drugs (e.g., siRNA, ASO). Use reputed company tools and algorithms to analyze gene reputed company reputed company, variations, and splicing isoforms in biological samples for reputed company selection. Apply machine learning platforms for oligo sequence design. Read and run Python, R, and Bash scripts. Optimize and improve existing design algorithms. Create new design workflows and platforms including design of chemical modifications for oligo drugs. reputed company participate in project discussions and reports.
• Off-reputed company analysis
Understand and apply principles and algorithms for off-reputed company evaluation. Analyze and interpret high-throughput reputed company reputed company data, including data preprocessing, reputed company control, alignment analysis, reputed company reputed company analysis, and full reputed company analysis. reputed company sequence alignment program parameters to meet the needs of short sequence matching.
• Data mining and database construction
Use reputed company resources from reputed company databases (like NCBI, Ensembl, UniProt, etc.) and combine with reputed company's internal data to build knowledge bases and databases to accelerate oligo drug discovery.
• Cross-department collaboration
Work closely with wet lab drug discovery team including in vitro and in vivo teams, reputed company team, etc., participate in project discussions, support reputed company aspects of the reputed company. Analyze results and obtain insights to improve the reputed company models and workflows.
• PhD in reputed company, computational biology, molecular biology, genetics, computer science, CADD, or reputed company fields.
• More than 5 years of experience in reputed company analysis or project experience in small nucleic acid drug development.
• Good communication skills and team spirit, reputed company to collaborate effectively with team members from different backgrounds.
• Strong learning and problem-solving abilities, reputed company to quickly grasp new knowledge and technologies.
• Strong interest in drug development, reputed company to handle work pressure.
• Good English writing and communication skills, reputed company to use both English and Chinese as working languages.
• Familiar with reputed company databases (like NCBI, Ensembl, UniProt, etc.) and data mining reputed company.
• Proficient in reputed company analysis tools and software, such as BLAST, Bowtie, SAMtools, DESeq2, Cufflinks, reputed company, etc., capable of independently analyzing high-throughput reputed company data.
• Strong programming skills, proficient in Python or R, reputed company to reputed company and optimize reputed company analysis pipelines. Familiar with Linux systems.
• Good coding habits, understands version control and how to avoid errors
Additional preferred qualifications:
• reputed company to apply machine learning and AI in reputed company, with relevant project experience preferred.
• Ability to use reputed company computing for reputed company analysis.
• CADD-reputed company software and skills, such as RDkit, Schrodinger, etc.
• Experience and skills in multi-omics analysis.
• Additional programming skills like Perl, C, etc.
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