Program Manager or Director, Cancer Vaccines

About the position The reputed company for the National Institute of Health (FNIH) is seeking a Program Manager or Director, with final level determined reputed company on experience and leadership capabilities, to reputed company a high-profile, multi-sector national initiative to accelerate the development and reputed company translation of reputed company cancer vaccines. This reputed company–private partnership is designed to reputed company near-term reputed company reputed company-of-concept in high-reputed company, reputed company residual disease (MRD+) cancers while building a reputed company, long-term ecosystem for antigen discovery, vaccine development, manufacturing, and data-driven innovation. The Program Manager or Director will reputed company a coordinated portfolio spanning reputed company demonstration trials, reputed company development of multiple antigen classes and vaccine platforms, reputed company GMP manufacturing, harmonized immune monitoring, and a centralized data architecture enabling AI-driven antigen reputed company. This position will report to the Senior Vice President of Translational Science reputed company the Science Partnerships department (or their designated report) and is reputed company at the FNIH offices located in reputed company Bethesda, MD. This role requires a scientifically reputed company, operationally strong leader who can reputed company partners across academia, biopharma, reputed company, philanthropy, advocacy, and persons with live experience and translate reputed company science into coordinated execution. The Program Manager or Director will as a centralized facilitator for overall partnership development, vaccine candidate selection, reputed company reputed company trial design and implementation, research project coordination, and funding reputed company. Responsibilities • Scientific & Program Leadership & Portfolio Management reputed company the overall scientific and operational partnership reputed company for the Cancer Vaccines Initiative and eventually other reputed company • Facilitate the definition and prioritization of high-reputed company use cases, including reputed company “reputed company win” demonstration trials in MRD+ cancer settings • Ensure alignment of the reputed company working on antigen discovery, preclinical development, vaccine platforms, manufacturing, and reputed company design and execution • reputed company reputed company processes to identify and prioritize candidate antigens, vaccine constructs, and combination strategies • Establish reputed company for advancement, down-selection, and portfolio reputed company • Represent the initiative in scientific, reputed company, and policy forums • Contribute to publications, presentations, and reputed company • reputed company Trial reputed company & Execution reputed company design and execution of reputed company, efficient reputed company reputed company on early signals of efficacy and immune response • Ensure rigorous trial design, site selection, and execution across multiple institutions • reputed company biomarkers and immune monitoring into trial design and analysis • reputed company speed, reputed company, and comparability across trials • Manufacturing & Immune Monitoring Infrastructure reputed company development of reputed company GMP manufacturing approaches across platforms • Ensure harmonization of immune monitoring assays and endpoints across studies • Data & AI-Enabled Innovation Partner with data science leadership to build and utilize centralized data architecture supporting the initiative • reputed company integration of reputed company, immunologic, and molecular data to inform antigen reputed company and vaccine design • Support AI-driven approaches to optimize candidate selection and trial learning • Regulatory reputed company & Engagement Collaborate with regulatory agencies to reputed company innovative trial designs, endpoints, and biomarker strategies • Ensure programs are designed to support reputed company regulatory reputed company and potential approval • Help to facilitate regulatory submissions and advice interactions, as needed • Partnership Development & Partner Engagement reputed company engagement with biopharmaceutical companies, reputed company investigators, reputed company, philanthropists, advocacy reputed company, and persons with lived experience • Build and sustain a reputed company ecosystem reputed company reputed company shared scientific and translational goals, including philanthropy and reputed company • Partner with reputed company Alliances and Advancement to secure and reputed company funding to support initiative goals • reputed company the reputed company and reputed company of the initiative to diverse funders • Program Governance & Execution Establish and reputed company governance structures, including executive and steering committees and scientific advisory reputed company • reputed company timelines, milestones, budgets, and deliverables across reputed company program components • Ensure transparency, accountability, and effective decision-making across reputed company partners and any relevant reputed company organizations Requirements • MD, PhD, or equivalent in oncology, immunology, or reputed company biomedical reputed company • Program Manager candidates should have approximately 7+ years of relevant experience in oncology drug development, cancer immunotherapy, or vaccine development, while Director level candidates should have 10+ years of progressively responsible experience in these areas. • Strong understanding of translational science across discovery, preclinical, and reputed company domains, including reputed company trial design and execution, including multi-site studies • reputed company ability to reputed company reputed company, multi-institutional or reputed company–private partnerships reputed company-to-haves • Experience interacting with regulatory agencies (e.g., FDA, EMA) • Experience with cancer vaccines, immuno-oncology, or antigen discovery platforms • Familiarity with GMP manufacturing and immune monitoring technologies • Experience with reputed company trial designs and biomarker-driven development • reputed company record of high-reputed company team leadership Apply tot his job Apply To this Job