[Remote] Computational Biologist II

Note: The job is a remote job and is open to candidates in USA. RefinedScience is dedicated to advancing care by integrating science and data to uncover pathways to better health. They are seeking a Computational Biologist II to perform bioinformatics analyses, collaborate with teams, and contribute to research initiatives using established methods on evolving datasets. Responsibilities • Execute bioinformatics and computational biology analyses with guidance from project and team leads • Collaborate effectively with bioinformatics colleagues, cross-functional teams, and external partners • Apply established methods to new and evolving datasets • Document analyses using reproducible research practices • Contribute to scientific reports and presentations • Participate in code reviews and team knowledge-sharing • Continuously learn new tools and approaches to support high-quality, scalable research and analytics initiatives at RefinedScience Skills • PhD in bioinformatics, computational biology, molecular biology, genomics, biostatistics, computer science, or related quantitative discipline (OR Master's with 2+ years relevant experience) • Proficiency in R or Python for data analysis and visualization • Familiarity with Linux/Unix command-line environments • Proficiency with Git/GitHub • Experience working with large-scale biological datasets • Exposure to conda, Docker, or similar tools • Training in and/or demonstrated ability to analyze and extract biological insights from single-cell datasets (e.g., scRNA-seq, ATAC-seq, CITE-seq, or other multi-omics data) • Understanding of next-generation sequencing technologies and data processing workflows • Solid understanding of statistical methods for biological data analysis (hypothesis testing, differential expression, dimensionality reduction, clustering, etc.) • Strong understanding of molecular biology principles; familiarity with cancer biology, immunology, hematology, or other relevant disease areas • Demonstrated independent research through doctoral thesis work • Author or co-author on peer-reviewed publications (submitted or published) • Experience presenting research findings at lab meetings, seminars, or conferences • Proven ability to formulate research questions, design analytical approaches, and troubleshoot complex data analysis challenges • Experience with single-cell analysis frameworks (Seurat, scverse, Bioconductor packages) • Familiarity with applying AI/ML methods and tools to computational biology tasks • Familiarity with pandas, numpy, scikit-learn, or similar libraries commonly used for data science and scientific computing • Exposure to cloud computing platforms (GCP) • Understanding of experimental design for genomics studies • Strong project and time management skills • Excellent written and verbal communication skills • Collaborative mindset and willingness to share knowledge and support team members • Prior experience working in Biotech or Pharma environment Company Overview • RefinedScience uses data, technology, and expertise to accelerate drug development. It was founded in 2019, and is headquartered in Aurora, Colorado, USA, with a workforce of 11-50 employees. Its website is https://www.refinedscience.com/. Company H1B Sponsorship • RefinedScience has a track record of offering H1B sponsorships, with 1 in 2025, 1 in 2023. Please note that this does not guarantee sponsorship for this specific role. Apply tot his job Apply To this Job