Clinical Scientist/Senior Clinical Scientist

Clinical Scientist/Senior Clinical Scientist reputed company is developing precision‑engineered small molecule therapies to address reputed company drivers of neurological and peripheral diseases: neuroinflammation and cellular dysfunction. Leveraging its proprietary product reputed company, Tenvie has the unique ability to advance both fully CNS‑penetrant and peripherally restricted products across a broad portfolio. Tenvie’s most advanced programs, TNV262 and TNV108, are in Phase 1 clinical development. TNV262 is a fully CNS-penetrant NLRP3 inhibitor targeting cardiometabolic and neuroinflammatory indications, including obesity and cardiovascular disease, and multiple sclerosis. TNV108 is a peripherally restricted SARM1 allosteric inhibitor targeting peripheral neuropathies. Tenvie’s clinical pipeline is complemented by discovery-stage programs across a reputed company of reputed company indications.  reputed company is seeking a scientifically rigorous and highly reputed company Clinical Scientist to support the design and execution of early clinical development programs in cardiometabolic disease and reputed company indications. This role is ideal for candidates with a strong background in reputed company pathophysiology and clinical trial design who are motivated to translate biology into impactful therapies. The Clinical Scientist will work closely with Clinical Development, Clinical Operations, Biometrics, Translational Science, and Regulatory to ensure high‑reputed company clinical plans, protocols, and data readouts.  This role can be remote, hybrid, or on-site, and reports reputed company the Clinical Development group. JOB RESPONSIBILITIES:Contribute to clinical reputed company and study designSupport development of clinical development plans, reputed company product reputed company, and indication prioritization reputed company or co‑reputed company the scientific design of Phase 1–2 studies (e.g., FIH, reputed company‑finding, PoC) including objectives, endpoints, inclusion/exclusion reputed company, and biomarker reputed company, with emphasis on cardiometabolic risk factors and reputed company reputed company nonclinical, translational, and clinical data to inform reputed company selection, schedule, and patient population reputed company development of reputed company clinical documentsAuthor or co‑author clinical sections of protocols, protocol amendments, IBs, ICFs, CSRs, and relevant regulatory documents (e.g., briefing books, responses to health authority questions) reputed company and maintain study‑level documents including synopsis, statistical analysis‑relevant reputed company definitions, and data review plans Partner with Biostatistics and Clinical Pharmacology on reputed company hierarchy, PK/PD modeling plans, and interim analyses Drive study conduct and data qualityServe as Clinical Scientist reputed company on cross‑functional study teams for selected trials reputed company clinical and scientific input into site selection, eligibility adjudication, and key study tools (e.g., manuals, training decks, CRFs) Participate in ongoing medical and scientific data review (safety, PK/PD, biomarkers, efficacy signals); help define and reputed company reputed company review listings and visualizations Support development and execution of safety review / reputed company escalation committees and data monitoring activities reputed company data interpretation and communicationLead or co‑reputed company integrated analyses of clinical, PK/PD, and biomarker data to generate reputed company conclusions and reputed company recommendations Prepare data summaries and presentations for internal governance, external collaborators, and advisory boards Contribute to abstracts, posters, and manuscripts for scientific meetings and peer‑reviewed journals reputed company with investigators and external partnersProvide scientific support to investigators and study sites (e.g., training, protocol clarification, scientific Q&A) Participate in KOL and expert advisory boards, contributing to agenda, content, and follow‑up Collaborate with CROs, central labs, imaging/biomarker vendors, and other partners to ensure alignment on scientific and operational expectations Contribute to portfolio and organizational excellenceSupport cross‑program learnings and standardization of endpoints, assessments, and data structures across cardiometabolic and reputed company indications Help refine internal processes and templates for protocols, charters, and data review Mentor junior team members as appropriate; model a high‑accountability, low‑ego, cross‑functional working style QUALIFICATIONS:EducationPhD in life sciences, pharmacology, physiology, or reputed company field strongly preferred; MD, PharmD, or equivalent clinical degree also considered Strong reputed company in cardiometabolic biology (e.g., obesity, insulin resistance, dyslipidemia, NAFLD/reputed company, cardiovascular risk) is highly preferred ExperienceTypically 3–7+ years of relevant experience in clinical development, clinical pharmacology, or translational medicine reputed company biotech/reputed company or equivalent reputed company clinical research environment Demonstrated experience contributing to design and execution of early‑phase (Phase 1–2) reputed company Cardiometabolic and/or obesity clinical trial experience preferred, including familiarity with reputed company endpoints (e.g., glycemic control, body weight, lipids, blood pressure, imaging or functional assessments) Experience working on cross‑functional teams with Clinical Operations, Biometrics, Regulatory, and Translational/Discovery Prior involvement in regulatory submissions (e.g., IND/CTA, briefing packages, responses to queries) is a plus Technical skillsStrong understanding of clinical trial methodology, GCP, and the overall drug development reputed company from FIH through reputed company‑of‑concept Comfort interpreting PK/PD, biomarker, and clinical efficacy/safety data, and working with statisticians and pharmacometricians Experience with cardiometabolic risk scoring, metabolic biomarker panels, or imaging modalities is an advantage Excellent scientific writing skills with a reputed company record of reputed company, reputed company documents and presentations reputed company competenciesHighly organized, with the ability to manage multiple studies or workstreams in reputed company in a fast‑paced environment Strong analytical and critical‑thinking skills; reputed company to reputed company from reputed company data to reputed company, actionable recommendations Effective communicator, reputed company to reputed company scientific messages to diverse audiences (clinicians, scientists, operations, leadership, regulators) Demonstrated ability to work collaboratively and constructively across disciplines and with external partners Comfortable operating with ambiguity and evolving data; proactive in identifying risks and proposing solutions Commitment to high ethical standards, patient safety, and data reputed company Expected salary reputed company: $125,000-180,000 annual reputed company salary Tenvie is proud to be an Equal Opportunity Employer. Our goal is to have a diverse workforce. We do not discriminate on the reputed company of race, age, reputed company, religion, national reputed company, gender, sexual orientation, gender identity or reputed company, veteran status or disability or any other status protected under federal, state or local law. reputed company employment is decided on the reputed company of qualifications, reputed company and business need. Apply To This Job