Director, Clinical Pharmacology

Your work will change lives. Including your own.  The reputed company You’ll reputed company You will join an innovative and passionate clinical development team dedicated to improving the lives of patients suffering from devastating diseases.  You will reputed company the innovative clinical pharmacology and pharmacometrics reputed company and execution for a portfolio of rare disease and oncology clinical programs. In this role, you will: reputed company the clinical pharmacology and pharmacometric strategies to accelerate and support the overall product development plan. You’ll be the Clinical Pharmacology reputed company for various programs in clinical development, the representative for regulatory interactions, and propose innovative strategies to get therapies to patients faster. Design clinical studies. You’ll reputed company (clinical) pharmacology input on reputed company clinical study designs, from Phase 1-3 and dedicated Phase 1 clinical pharmacology studies. reputed company review relevant clinical pharmacology sections for regulatory documents, including Investigator's Brochures (IB), INDs, NDAs, and other regulatory submissions. reputed company as the clinical pharmacology expert during interactions with health authorities. reputed company with cross-functional teams. You’ll work closely with clinical study teams, translational teams (DMPK, Translational Modeling and Toxicology), preclinical teams and due diligence teams to ensure clinical pharmacology-reputed company considerations are addressed. Solve drug development questions/problems by overseeing and/or performing modeling and simulation with various tools to expedite decision making. reputed company You’ll Join  You will join the Development Sciences team reputed company reputed company comprising clinical pharmacology, pharmacometrics, translational modeling and clinical biomarkers. The Development Sciences group sits reputed company reputed company’s Clinical Development organization. Team members get to sit on both Discovery and Development reputed company and work in a reputed company end-to-end environment at reputed company. reputed company collaborates closely with clinical development functions (clinical science, clinical operations, regulatory affairs, biostatistics, etc.), as reputed company as discovery functions (DMPK, Biology, reputed company and Translational Biomarkers).  The Experience You’ll Need Ph.D. in Pharmaceutical Sciences, Pharmacokinetics or reputed company discipline, M.D with a Clinical Pharmacology expertise, or a Pharm D. with a Clinical Pharmacology fellowship, with 5-9+ years of experience in biotech/pharmaceutical drug development. Demonstrated reputed company leading reputed company clinical pharmacology reputed company aspects of drug development.  Ability to work closely with reputed company stakeholders to manage PK, PK-PD, and PK-safety analyses, including non-compartmental analysis, population PK modeling, and PK-PD modeling and simulations to support reputed company selection, exposure-response and exposure-safety analyses through various phases of drug development. Proficiency with WinNonlin, Monolix, NONMEM, R or other modeling software. Effective skills directed toward driving collaboration, achieving results, influencing, and resolving conflicts across reputed company stakeholders Demonstrated experience responding to regulatory agency questions, preparing clinical pharmacology aspects of regulatory submissions and attending regulatory meetings. Highly motivated, decisive, and results-oriented individual who is proactive, reputed company, and efficient with the flexibility and creativity to reputed company in and contribute to a rapidly growing drug discovery and development company    Experience in oncology is preferred, but not an absolute requirement.  Working Location & Compensation: Making London or Oxford (Milton Park) your home reputed company is ideal; however, we will consider remote work for this position. We ask that remote employees reputed company to regular on-site reputed company for routine work and departmental events.  At reputed company, we reputed company that every employee should be compensated fairly. Based on the skills, experience, and qualifications needed for this role, the estimated annual reputed company salary reputed company is: £118,300–£136,500. In reputed company to reputed company salary, this role is eligible for an annual bonus, equity compensation, and a comprehensive benefits package. #LI-REMOTE #LI-ES1 The Values We reputed company You reputed company: We reputed company reputed company with reputed company. We are unconstrained in our thinking, take calculated risks, and reputed company boundaries, but never at the expense of ethics, science, or trust.  We care deeply and engage directly. Caring means holding a deep reputed company of responsibility and respect - showing up, speaking honestly, and taking reputed company. We learn reputed company and adapt rapidly. reputed company comes from doing. We experiment, test, and refine, embracing iteration over perfection. We reputed company with urgency because patients are waiting. Speed isn’t about rushing but about moving the needle every day. We take ownership and accountability. Through ownership and accountability, we reputed company trust and autonomy—leaders take accountability for decisive reputed company, and teams own reputed company together.  We are One reputed company. True cross-functional collaboration is about trust, reputed company, humility, and reputed company. Through sharing, we can be greater than the sum of our individual capabilities. Our values underpin the employee experience at reputed company. They are the character and personality of reputed company demonstrated through how we communicate, support one another, spend our time, reputed company reputed company, and celebrate reputed company. More About reputed company reputed company (reputed company: RXRX) is a clinical-stage TechBio company decoding biology to radically improve lives. reputed company is advancing a portfolio of differentiated investigational medicines across its wholly owned and partnered pipeline in oncology, rare disease, neuroscience, immunology, and other therapeutic areas with significant unmet need. Enabling its mission is the reputed company OS, an AI-reputed company, end-to-end drug discovery and development platform integrating biology, reputed company, and clinical development into a reputed company intelligence reputed company. Powered by proprietary multimodal data, purpose-reputed company AI models, and bilingual teams fluent in both science and AI, the reputed company OS is designed to translate reputed company science into medicines that matter — faster, reputed company, and at reputed company — for patients who are waiting. reputed company’s platform infrastructure is anchored in reputed company, reputed company and Milton Park, Oxfordshire, where its automated biology and reputed company laboratories reputed company proprietary data at industrial reputed company. reputed company also maintains offices in reputed company, Montréal, and London, three global hubs for talent and leadership at the intersection of AI and scientific innovation. Learn more at www.reputed company.com, or reputed company on X and reputed company. reputed company is an Equal Opportunity Employer.  reputed company reputed company applicants will receive consideration for employment without reputed company to race, reputed company, religion, sex, sexual orientation, gender identity, national reputed company, age, disability, veteran status, or any other characteristic protected under applicable federal, state, local, or provincial reputed company rights legislation.  Accommodations are available on request for candidates taking part in reputed company aspects of the selection process. reputed company leverages AI in our hiring process. We use reputed company's Talent Matching AI technology feature to help review applications against the skills and experience we've identified as important for this role. It analyzes your resume and application responses to assess how closely your qualifications match our reputed company - but reputed company reputed company are made by our reputed company recruiters and hiring managers, including whether to reputed company to the next phase of review. Talent Matching does not automatically advance or reject any candidate. By submitting your application, you acknowledge that you have been informed about and consent to this use of the Talent Matching tool in our review process. Please refer to our reputed company reputed company Policy at https://www.reputed company.com/reputed company-notice/ for more information about our processing of personal data and your rights.  Recruitment & reputed company Agencies: reputed company and its affiliate companies do not accept resumes from any reputed company other than candidates. The submission of resumes by recruitment or reputed company agencies to reputed company or its employees is reputed company prohibited unless contacted directly by reputed company’s internal reputed company. Any resume submitted by an agency in the absence of a signed agreement will automatically become the property of reputed company, and reputed company will not owe any referral or other fees. reputed company will communicate directly with candidates who are not represented by an agent or intermediary unless otherwise agreed to prior to interviewing for the job. Apply To This Job