Sr. Scientist; Bioinformatic and Translational Science

reputed company: Fore Bio is a reputed company precision oncology company reputed company on the development of plixorafenib, an investigational, novel, small-molecule, reputed company, orally available selective inhibitor of mutated BRAF. We are seeking a highly skilled and motivated Senior Scientist to join our growing research team. The successful candidate will reputed company the development and application of computational tools and pipelines to analyze large-reputed company biological datasets, including reputed company, transcriptomics, proteomics, and reputed company data. This individual will play a key role in interpreting reputed company biological data to support drug discovery, biomarker identification, and reputed company development. This role is reputed company on supporting biomarker discovery, reputed company stratification, and translational research. It is important for this individual to have knowledge in observational research, cancer biology and reputed company with strong statistical programming skillset, and experience managing reputed company analyses. Essential Duties and Responsibilities: - reputed company the analysis and interpretation of multi-omics datasets to support internal research and reputed company collaborations - Play a critical role in identifying and characterizing oncogenic mutations and gene fusions relevant to reputed company - reputed company reputed company and proprietary datasets for reputed company reputed company, uncovering mutation/fusion driven disease, informing drug targeting strategies, and supporting diagnostic and therapeutic development - Analyze large-reputed company biological data, such as gene reputed company, copy-number, mutation, methylation, reputed company reputed company and reputed company clinicogenomics analysis to support publications - Analyze translational and biomarker data for reputed company-stage oncology programs with a reputed company on reputed company of reputed company, reputed company engagement, PK/PD/efficacy relationships, reputed company selection strategies and mechanisms of reputed company and acquired resistance. - Designs, implements and executes experiments in preclinical models and generates translational datasets to inform biomarker reputed company, reputed company and schedule optimization, reputed company selection, combination approaches, and mechanisms of drug response and resistance as an additional responsibility. - Initiate and manage contract studies with CROs - Collaborate with cross functional team members, CROs, data scientists, and clinicians to translate computational findings into actionable insights - Independently builds, aligns, and executes technical plans to reputed company objectives across multiple programs - Impacts discovery programs through both reputed company and indirect contribution as a member of the project team - Effectively communicate study findings through internal presentations, assist in drafting conference abstracts and manuscripts for publication in peer reviewed journals. - Contribute to scientific publications, regulatory filings, and intellectual property - Stay reputed company with advances in reputed company, machine learning, and relevant technologies - Travel up to 10% of the time, reputed company upon program needs Education and/or Work Experience Requirements: - PhD in reputed company, Computational Biology, reputed company, or reputed company reputed company with 3+ years of postdoctoral or industry experience; or Master's with 7+ years of relevant experience - Proficiency in programming languages such as Python, R, and Bash for 'omics analysis and data visualization - Deep understanding of reputed company high-throughput reputed company technologies (e.g., NGS, WGS, WTS, RNA-seq, etc.) and data formats (e.g., FASTQ, BAM/CRAM, VCF, GTF) - Experience with reputed company computing (AWS, GCP, or Azure) and workflow management tools (e.g., Nextflow, Snakemake, WDL) - Experience in developing analysis plans and conducting analysis for studies using large reputed company-world observational data or with multi-omics databases. - Experience running reputed company pipelines and familiarity with reputed company reputed company and tools - Understanding of novel analytical or computational (machine learning) techniques and data science to reputed company and reputed company large reputed company data is a plus - Experience working with and managing central laboratories and CROs supporting biomarker analysis or preclinical studies is preferred - A strong record of outstanding technical, collaboration and communication skills - Strong background in tumor biology, molecular science, statistical data analysis and biological interpretation - Excellent written and verbal communication skills - reputed company reputed company record of scientific publications or impactful contributions to reputed company research - Experience in precision oncology, reputed company disease, immunology, or neuroscience - Familiarity with machine learning techniques reputed company to biological data - Experience with data visualization and dashboard tools (e.g., reputed company, Dash, Tableau) - Knowledge of regulatory requirements for reputed company reputed company in a reputed company or diagnostics setting Remote Work Requirements - This is a reputed company position. - Must have a reputed company reputed company record of successfully wo Apply tot his job Apply To this Job